PA DOH: Severe Manifestations of Monkeypox among People who are Immunocompromised Due to HIV or Other Conditions

The Pennsylvania Department of Health released a health advisory on October 4, 2022. Below is a summary:

Severe Manifestations of Monkeypox among People who are Immunocompromised Due to HIV or Other Conditions

  • Severe manifestations of monkeypox have been observed in the United States in the current outbreak.
  • People who are immunocompromised due to HIV or other conditions are at higher risk for severe manifestations of monkeypox than people who are immunocompetent.
  • Because people with HIV-associated immunocompromise are at risk for severe manifestations of monkeypox, the HIV status of all sexually active adults and adolescents with suspected or confirmed monkeypox should be determined.
  • There are diagnostic and clinical management strategies that may help address severe manifestations of monkeypox including: oral and intravenous tecovirimat (TPOXX), cidofovir or brincidofovir, and vaccinia immune globulin intravenous (VIGIV).
  • Contact your local health department or the PA Department of Health (PADOH) at 717-787-3350, when there is concern for progression to severe manifestations or severe manifestations are present for guidance on management and securing necessary resources for treatment.

Click here to view the full health advisory from the PA DOH website (PDF)

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